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Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
Imatinib Mesylate Im, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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96
Selleck Chemicals imatinib im
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
Imatinib Im, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/imatinib+%28im%29/pm40724843-174-3-26?v=Selleck+Chemicals
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Novartis imatinib im
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
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96
Selleck Chemicals tcr pathway inhibitor imatinib mesylate im
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
Tcr Pathway Inhibitor Imatinib Mesylate Im, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Novartis imatinib (im, glivec, novartis)
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
Imatinib (Im, Glivec, Novartis), supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Selleck Chemicals disulfiram s1680
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
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93
MedChemExpress imatinib im
Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or <t>imatinib</t> (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.
Imatinib Im, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or imatinib (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.

Journal: International Journal of Molecular Sciences

Article Title: Claudin-1 Contributes to Gastrointestinal Stromal Tumors (GIST) Resistance to Imatinib Mesylate (IM) via Regulation of FGFR-Signaling

doi: 10.3390/ijms26178138

Figure Lengend Snippet: Inhibition of CLDN1 with PDS-0330 in GIST T-1R and GIST 430 cells. GIST T-1R ( A ) and GIST 430 ( B ) cells were treated with PDS-0330 (5 µM) or imatinib (IM) (1 µM) alone or in combination for 72 h and subjected to western blotting analysis to examine the expression of apoptotic markers, such as cleaved forms of PARP and caspase-3, phospho-KIT Y719, and c-KIT. Actin staining was used to show the comparable amounts of protein loaded into each sample.

Article Snippet: Imatinib mesylate (IM) and PDS-0330 were obtained from Selleck Chem (Houston, TX, USA).

Techniques: Inhibition, Western Blot, Expressing, Staining